Exact switch and attachment of a single nanowire to a goal substrate is an attention-grabbing approach in floor engineering. The spacing, which restrains the attachment of a nanowire to a substrate, and the bending pressure that happens when the nanowire detaches from the elastomeric donor are necessary design parameters. On this regard, on this research, all-atom molecular dynamics (MD) simulations have been carried out to analyse the mechanical behaviour of a penta-twinned silver nanowire (AgNW) positioned on a polydimethylsiloxane (PDMS) donor substrate to elucidate the related switch course of. The bow deformation of the AgNW on the delamination entrance of PDMS was characterised as a perform of its diameter and side ratio. The mechanisms of dislocation slip and propagation in addition to the interior stress distribution of the AgNW have been then examined. The outcomes confirmed that twin boundary formation through the bow deformation is a key issue affecting the pressure hardening of the AgNW and main to finish plastic pressure restoration after the removing of the PDMS substrate. Moreover, the method was demonstrated experimentally by a localized bonding and switch of AgNWs by continuous-wave laser irradiation. Primarily based on the computational and experimental findings, an empirical mannequin contemplating the form parameters of AgNWs that may guarantee a profitable switch course of was established, which is crucial for high-performance AgNW electrode design.